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Peptide: GHRP-6

GHRP-6, or Growth Hormone-Releasing Peptide 6, is a synthetic peptide that belongs to a class of compounds known as growth hormone secretagogues. It stimulates the release of growth hormone (GH) from the pituitary gland in the brain.


Here are some key points about GHRP-6:

  1. Mechanism of Action: GHRP-6 acts by binding to a specific receptor called the growth hormone secretagogue receptor (GHS-R) in the brain. This interaction triggers the release of growth hormone from the pituitary gland.

  2. GH Stimulation: GHRP-6 induces the secretion of growth hormone in a dose-dependent manner. It mimics the action of the natural peptide ghrelin, which also stimulates GH release.

  3. Potential Benefits: GHRP-6 has been studied for its potential therapeutic applications. Some of the reported benefits include increased muscle mass, improved strength and endurance, enhanced fat burning, and potential wound healing properties.

  4. Appetite Stimulation: GHRP-6 has been found to increase appetite in humans, which can be advantageous in certain medical conditions where increased food intake is desired, such as cachexia or certain eating disorders.

  5. Side Effects: Like any therapeutic compound, GHRP-6 may have side effects. Some reported side effects include increased hunger, water retention, tingling or numbness in the extremities, drowsiness, and potential insulin resistance with long-term use. It's important to note that the information on side effects is based on limited research and individual experiences.

  6. Research and Regulation: GHRP-6 is a subject of ongoing research, primarily in the field of growth hormone deficiency, muscle wasting disorders, and performance enhancement. Its use as a performance-enhancing drug in sports is prohibited by most sports organizations and is classified as a prohibited substance.

  7. Caveat: The consumption of carbohydrates and/or dietary fats, around the administration window significantly blunts the GH release.

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